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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FEN1
All Species:
22.42
Human Site:
S317
Identified Species:
44.85
UniProt:
P39748
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39748
NP_004102.1
380
42593
S317
M
C
G
E
K
Q
F
S
E
E
R
I
R
S
G
Chimpanzee
Pan troglodytes
XP_001149490
346
39044
L284
K
E
A
H
Q
L
F
L
E
P
E
V
L
D
P
Rhesus Macaque
Macaca mulatta
XP_001118506
412
46252
L350
K
E
A
H
Q
L
F
L
K
P
E
V
L
D
P
Dog
Lupus familis
XP_533271
380
42605
S317
M
C
G
E
K
Q
F
S
E
E
R
I
R
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P39749
378
42296
S315
M
C
G
E
K
Q
F
S
E
E
R
I
R
S
G
Rat
Rattus norvegicus
NP_445882
380
42603
S317
M
C
G
E
K
Q
F
S
E
E
R
I
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001072959
381
42965
N317
M
C
G
E
K
Q
F
N
E
E
R
I
R
N
G
Frog
Xenopus laevis
P70040
382
42650
S317
M
C
G
E
K
Q
F
S
E
D
R
I
R
N
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523765
385
42930
N317
L
C
G
D
R
Q
F
N
E
E
R
V
R
N
G
Honey Bee
Apis mellifera
XP_395769
379
42891
N317
L
C
G
D
K
Q
F
N
E
E
R
V
R
N
G
Nematode Worm
Caenorhab. elegans
NP_491168
382
42531
N317
L
C
G
E
K
N
F
N
E
E
R
I
R
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P26793
382
43261
S320
L
C
D
D
K
K
F
S
E
E
R
V
K
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
83.2
98.1
N.A.
95.5
95.7
N.A.
N.A.
84.2
79.8
N.A.
N.A.
62.5
62.3
61.2
N.A.
Protein Similarity:
100
91
83.9
99.2
N.A.
97.1
98.4
N.A.
N.A.
93.1
90.8
N.A.
N.A.
78.9
80.2
76.6
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
N.A.
N.A.
60
66.6
66.6
N.A.
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
56.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
25
0
0
0
0
0
9
0
0
0
17
0
% D
% Glu:
0
17
0
59
0
0
0
0
92
75
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
75
% G
% His:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
59
0
0
0
% I
% Lys:
17
0
0
0
75
9
0
0
9
0
0
0
9
0
0
% K
% Leu:
34
0
0
0
0
17
0
17
0
0
0
0
17
0
0
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
34
0
0
0
0
0
42
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
17
% P
% Gln:
0
0
0
0
17
67
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
84
0
75
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
0
0
42
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _